Molecular Switching in Human Adenovirus

Molecular Investigation of the Human Adenovirus in Retinoblastoma Patients

Background and Aims: Retinoblastoma tumors are the most common intraocular malignancy in childhood, leading to death after two years. The Human Adenovirus (HAdV) infection could be critical in the retinoblastoma pathogenesis due to the virus and retinoblastoma 1 interactions. The objective of the current study was to investigate the possible presence of the HAdV genome in the retinoblastoma pat...

Molecular monitoring effectiveness of human adenovirus removal in Isfahan water treatment plant

Background and Objective: Human adenoviruses transmitted from contaminated water are one of the major pathogens that has been introduced as one of the most important new qualitative water indicators due to their resistance against the purification processes. The main objective of this study was to evaluate efficiency of human adenovirus removal in different units of Isfahan Water Treatment Plan...

Epidemiology of human adenovirus and molecular characterization of human adenovirus 55 in China, 2009–2012

BACKGROUND Human adenovirus 55 (HAdV-55) has caused recent outbreaks of acute respiratory disease (ARD) among adults and military trainees. The active surveillance for HAdV infections was sparse in China, and current knowledge on the HAdV-type distributions and its molecular evolution is lacking. OBJECTIVES To acquire better understanding on the prevalence and molecular evolution of HAdV-55 s...

The Occurrence of Adenovirus Precipitating Antibodies in Human Sera in IRAN

Production of Recombinant Adenovirus Containing Human Interlukin-4 Gene

Objective(s) Recombinant adenoviruses are currently used for a variety of purposes, including in vitro gene transfer, in vivo vaccination, and gene therapy. Ability to infect many cell types, high efficiency in gene transfer, entering both dividing and non dividing cells, and growing to high titers make this virus a good choice for using in various experiments. In the present experiment, a reco...